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Biography

Michael Lu, Ph.D., is an associate professor of biomedical science.

Education

• 1972: Intern, Infectious Disease, Veterinary Hospital, National Taiwan University, Taipei, Taiwan
• 1981: Resident, Veterinary Hospital, National Taiwan University, Taipei, Taiwan
• 1982: B.V.M., National Taiwan University, R.O.C.Ìý
• 1988: Ph.D., Molecular and Cellular Biology, University of Massachusetts, Amherst.

Work History

• 2006- Present: Associate Professor, Charles E. Schmidt College of Medicine, ´óÏó´«Ã½, Boca Raton, Florida
• 1992-2006: Director, Urologic Oncology Research, Brigham and Women's HospitalÌý
• 1994-2006: Assistant Professor, Department of Surgery, Harvard Medical School
• 1992-1994: Instructor, Department of Surgery, Harvard Medical School
• 1989-1990: Research Fellow, Neuromuscular Disease, Muscular Dystrophy Association
• 1988-1990: Postdoctoral Research Fellow, Pathology, Dana Farber Cancer Institute and Harvard Medical School

Scholarly Activity

Research Interests

• Hormone-regulated signal transduction
• Tumor metastasis
• Cell growth regulation

Peer-Reviewed Publications

• Jean-Philippe, J., Paz, S., Lu, M.L., Caputi, M. (2014). A truncated hnRNP A1 isoform, lackingÌýthe RGG-box RNA binding domain, can efficiently regulate HIV-1 splicing and replication.ÌýBiochim Biophys Acta, 1839(4), 251-8.
• Wang H, McNight NC, Zhang T,ÌýLu ML, Balk SP and Yuan X SOX9 is Expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells.ÌýCancer Res. 2007; In Press
• Yuan X, Li T, Wang H, Zhang T, Barua M, Borgesi RA, Buble GJ,ÌýLu MLÌýand Balk SP Androgen receptor remains critical for cell cycle progression in androgen independent CWR22 prostate cancer cells.ÌýAm. J. Path. 2006; 169: 682-696
• Jia Z, Zhang A, Barbier L, Vadnais J, Noel J,ÌýLu MLÌýand. Nabi IR. Autocrine c- Met/HGF-R activation of localized Rho/ROCK/p38 MAP kinase signaling directs the protrusion of tumour cell pseudopodia.ÌýBiol. CellÌý2006; 96:337-351
• Freeman MR, Cinar B andÌýLu ML. Membrane rafts as potential sites of nongenomic hormonal signaling in prostate cancer.ÌýTrens Endocrin. Metabol. 2005, 16:273-279
• Kaur R, Liu X, Gjoerup O, Zhang A, Balk SP, Yuan X, Schneider MC andÌýLu ML. Activation of p21 Activated Kinase (PAK6) by MAP kinase kinase 6 and p38 MAP kinase.ÌýJ. Biol. Chem.Ìý2005; 280:3323-3330.
• Mukhopadhyay NK, Gilchrist D, Gordon GJ, Chen C-J, Bueno R,ÌýLu ML, Salgia R, Sugarbaker DJ, Jaklitsh MT. Integrin Dependent Protein Tyrosine Phosphorylation is a Key Regulatory Event in Collagen IV Mediated Adhesion and Proliferation of Human Ling Tumor Cell Line, Calu-1. Thor.SurgeryÌý2004; 78:450-457.
• Wilbur A, O Connor TP,ÌýLu ML, Schneider MC. DNASE1L3 Deficiency in Lupusprone MRL and NZB/W F1 Mice.ÌýClin Exp ImmunolÌý2003; 134:46-52.